factoid # 110: around 80% of all livejournal users are from the united states of america. Interesting internet facts »    home   encyclopedia   statistics   countries a-z   flags   maps   education   forum   faq   about        what's new thank you, mr barton loads more stats on » compare any two countries » updated crime data! Making it super easy » recent articles list of famous scientologists history of virtual learning environments oneness pentecostalism oneness pentecostal usher syndrome#usher_syndrome_iii list of people who were executed weathering cambridge university conservative association michael peter woroniecki more recent articles  »   search all facts & statistics    advanced view search encyclopedia, statistics and forums:     select category agriculture background crime currency democracy disasters economy education energy environment food geography government health identification immigration industry internet labor language lifestyle media military mortality people religion sports taxation terrorism transportation (* = graphable)     encyclopedia > membranous glomerulonephritis jump to: navigation, search membranous glomerulonephritis (mgn), also known as membranous nephropathy is a slowly progressive disease affecting mostly patients between ages of 30 and 50 years. 85% of mgn cases are classified as primary membranous glomerulonephritis -- that is to say, the cause of the disease is idiopathic (unknown). The remainder is secondary due to : autoimmune conditions (e. G. , systemic lupus erythematosus) infections (e. G. , syphilis, malaria, hepatitis b) drugs (e. G. , captopril, nsaids) inorganic salts malignant tumors (in particular, carcinoma of the lung and colon, and melanoma) pathogenesis mgn is caused by circulating immune complex. Current research indicates that the majority of the immune complexes are formed via binding of antibodies to antigens in situ to the glomerular basement membrane. The said antigens may be endogenous to the basement membrane, or "planted" from systemic circulation. viagra without a doctor prescription viagra online cheap viagra online buy viagra online buy viagra cheap generic viagra generic viagra http://classicmotocrossimages.com/mbs-uk-viagra-sales-yg/ buy viagra buy cheap viagra The immune complex serves as an activator that triggers a response from the c5b - c9 complements, which form a membrane attack complex (mac) on the glomerular epithelial cells. This, in turn, stimulates release of proteases and oxidants by the mesangial and epithelial cells, damaging the capillar walls and causing it to become "leaky". In addition, the epithelial cells also seem to secrete an unknown mediator that reduce nephrin synthesis and distribution. Www. Mgninfo. Co. Uk morphology the defining point of mgn is the presence of subepithelial immunoglobulin-containing deposits along. what happens when you give women viagra